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Measuring disease progression is vital in the management of patients with glaucoma and ocular hypertension. |
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Progression may be assessed by structure (optic disc photography or semi-automated imaging devices) and function (perimetry). |
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Progression strategies may be subdivided into “event analyses” (progression requires a predetermined threshold to be exceeded)
and “trend analyses” (the behaviour of the parameter over time is monitored).
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Stereophotographic examination is prone to high inter-observer variability. |
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Amongst imaging devices, the HRT has the most published longitudinal data, as it has been commercially available for the longest
time and its software is “backward compatible”.
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Two progression algorithms are currently available in the HRT software: “trend analysis” and “topographical change analysis”. |
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To date there are no statistically supported progression algorithms in the OCT or GDx-VCC operational software. |
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There is poor concordance between HRT and visual field progression. The reasons for this remain unclear. |