Today’s GUIs and their familiar methods are far from optimal for typical users, wasting time, causing unnecessary errors, exacerbating repetitive stress injuries, and inducing frustration and annoyance. These problems are often amplified when standard interface methods are used in systems for less-abled users. We must not be distracted from good interface design by the straitjackets of present paradigms. To this end we employ insight, ingenuity, and testing – but they are not enough. Cognetic tools, which are quantitative and objective instead of being based on heuristics and subjective judgment, can play an important role in increasing accessibility, even where we use existing hardware.