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Club Jules Gonin

Orbital invasion despite topical anti-metabolite therapy for conjunctival carcinoma

Devron H. Char and J. Brooks Crawford

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Abstract

Background  

Two cases of conjunctival carcinoma developed orbital invasion during treatment with topical medication.

Methods  

This was a retrospective study from a tertiary ophthalmic oncology unit, performed after informed consent was obtained. The main outcome measurement was orbital invasion.

Results  

Two patients treated with topical agents developed orbital invasion.

Conclusion  

While topical agents are important in treatment of conjunctival neoplasia, recurrence or deep invasion require careful monitoring.

Keywords  Orbital invasion - Squamous cell carcinoma - Mitomycin - Topical medication

Supported in part by a grant from the Tumori Foundation. The author has no financial interest in the subject matter.

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