Experiments on rats showed that diazepam, in a dose of 10 mg/kg by mouth throughout pregnancy, affects the development of the offspring. Changes observed in the behavior of the young rats are evidently due to the activating action of the compound in small doses on the fetus after passing through the placental barrier.
Key Words diazepam - development of the offspring
Laboratory of General Pharmacology, Institute of Pharmacology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. V. Zakusov.) Translated from Byulleten'' Éksperimental''noi Biologii i Meditsiny, Vol. 78, No. 10, pp. 64–66, October, 1974.