The reactions of 4-(aminobenzenesulfonamide)-2-thiazole with the appropriate 8-benzodioxane aldehydes were used to synthesize
a series of new azoethines. The proposed structures are confirmed by IR and NMR spectroscopy. It is shown that the obtained
azomethines exhibit high (97–100%) activity against
Mycobacterium tuberculosis H37Rv at a concentration of 0.2–1.5 mg-mL
in vitro.
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 7, pp. 8–9, July, 2008.