This study investigated whether retinal capillary circulation in the macula is affected in exfoliation glaucoma and whether such changes can be detected in exfoliation syndrome without glaucoma. Blue-field entoptic simulation (measurement of macular capillary leukocyte velocity and density) was performed in 2 groups: 10 subjects with unilateral exfoliation glaucoma and 11 subjects with unilateral normotensive exfoliation syndrome. Macular capillary leukocyte velocity was reduced in exfoliation glaucoma but not in normotensive exfoliation syndrome.