Cellular and Molecular Life Sciences
Volume 37, Number 9, 933-934, DOI: 10.1007/BF01971761

Concurrent occurrence of elevated ketone body and depressed carnitine level in underfed guinea-pigs

A. Sandor, J. Kerner and I. Alkonyi

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Abstract

Food ingestion of male guinea-pigs was restricted to 10 g/day. Total carnitine content of liver of the underfed animals fell to 3.75 mgrmoles per liver (46.1% of control). Serum level of total carnitine was 35.0 nmoles/ml (64.4%) in the underfed animals while they developed high ketonemia, 384.2 nmoles/ml (555.2%). In lsquorestrictedrsquo animals the carnitine levels also decreased in the muscles.

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