This paper introduces the work of the COGAIN “communication by gaze interaction” European Network of Excellence that is working toward giving people with profound disabilities the opportunity to communicate and control their environment by eye gaze control. It shows the need for developing eye gaze based communication systems, and illustrates the effectiveness of newly developed COGAIN eye gaze control systems with a series of case studies, each showing differing aspects of the benefits offered by gaze control. Finally, the paper puts forward a strong case for users, professionals and researchers to collaborate towards developing gaze based communication systems to enable and empower people with disabilities.