In this paper we will show how fact-orientation can be used as a knowledge structuring approach for verbalizable knowledge domains, e.g. knowledge that is contained in articles, text books and instruction manuals further to be referred to as ‘subject matter’. This article will illustrate the application of the fact-oriented approach as a subject matter structuring tool for a small part of the sub-domains of operations management and marketing within the university subject of business administration. We will also show that the factoriented modeling constructs allow us to structure knowledge on the first five levels of Bloom’s taxonomy of educational objectives and we will show how the fact-oriented approach complies to the 4C/ID model for instructional design. Moreover, we will derive a ‘knowledge structure metrics’ model that can be empirically estimated and that can be used to estimate the complexity metric of a subject matter.