Volume 15, Number 2, 121-123, DOI: 10.1007/s12199-009-0112-y

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Development of a new disinfectant with very strong anti-influenza viral activity: a preliminary report

Hiroki Takakuwa, Toshiyuki Maruoka, Tadayo Hata, Masaaki Miyazawa, Tomoyo Hata, Hitoshi Toshimori and Koichi Otsuki

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Abstract

Objectives  

We evaluated the effectiveness and safety of a disinfectant newly developed by our laboratories for use against influenza viruses.

Methods  

The effectiveness of our new disinfectant against avian, swine and human influenza viruses was tested in ovo. The acute toxicity of this disinfectant to two different cultured cell lines was investigated.

Results  

This new disinfectant showed very strong anti-influenza viral activity in the in ovo tests. All of the influenza viruses tested were inactivated very quickly. Following exposure to the disinfectant, the infectivity of all viral strains tested had been eliminated within ≤10 min. The infectant showed a weak acute toxicity in vitro.

Conclusion  

This new disinfectant is expected to be useful for preventing viral infection during a new influenza pandemic.

Keywords  Avian influenza virus - Human influenza virus - New disinfectant - Strong activity - Swine influenza virus

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