Functionally substituted pyrrolothiazolidines have been synthesized by the sequential treatment of pyrrole-2-carbodithioates with methylene-reactive nitriles and haloacetylenes in a KOH-DMSO system.
haloacetylenes - CH-acids - pyrrole-2-carbodithioates - pyrrolothiazolidines - thiazines - halogenophilic attack - nucleophilic addition