The emergence of computational social science has had a transformative influence on the geographical sciences, integrating diverse themes of scholarship and allying it with the pursuit of grand challenges in the physical, natural, and life sciences. Geography has benefitted from many of these developments and has, in turn, catalyzed significant advances and innovation in computational social science. In this paper, I explore the relationship between geography, computing, and the social sciences by examining the evolution of some central themes in the computational social sciences: complexity, informatics, modeling and simulation, information visualization, cyberspace, socio-technical systems, and semantic computing.