Follow-up after endoscopic polypectomy should be led by the number, size, and histopatologic characteristics of the polyps at the baseline colonoscopy. In a patient with large sessile polyps and incomplete excision, a follow-up colonoscopy at 2-6 months is suggested. After curative resection of invasive carcinoma or malignant polyps, intense colonoscopy follow-up at 1 year is mandatory. Patients with high-grade dysplasia adenoma, villous histology, polyps larger than 10 mm, or more than three polyps have an intermediate risk of advanced neoplasia, and surveillance at 3 years is recommended. Patients with 1-2 small tubular adenomas should undergo surveillance colonoscopy at 5-10 years; in patients with negative or sporadic hyperplastic polyps at baseline colonoscopy, surveillance is now suggested after 10 years.