Volume 14, Numbers 5-6, 395-399, DOI: 10.1007/BF00163565

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Society for Ophthalmo-Immuno Infectiology in Europe

Cyclosporine-A in the treatment of serpiginous choroiditis

Antonio G. Secchi, M. Sofia Tognon and Cristina Maselli

From the issue entitled "Special issue on topics in uveitis"

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Abstract

Seven patients affected by bilateral inflammatory serpiginous choroiditis have been treated with Cyclosporine-A for 6-21 months. Nine outof the fourteen eyes showed a significant improvement in their visual acuity; five eyes did not change.
Cyclosporine-A may, therefore, be considered effective in the treatment of this disease.
Its usefulness seems to be greater when the serpiginous choroiditis is in its lsquoacutersquo stage; lsquochronicrsquo stages, however, also seem to improve under treatment.
Its main indication is, in our opinion, the involvement of the macular region of the lsquosecondrsquo eye, when the lsquofirstrsquo eye is already damaged. We consider Cyclosporine-A, in these situations, to be a first choice treatment.

Key words  Serpiginous choroiditis - geographic choroidopathy - Cyclosporine-A in uveitis - immunosuppression in uveitis

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