Volume 68, Number 2, 93-95, DOI: 10.1007/BF01715140

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Trisomy 21 as the sole clonal aberration in a patient with acute myelomonocytic leukemia with abnormal bone marrow eosinophils and extramedullary involvement

R. Dengler, J. -U. Walther and B. Emmerich

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Abstract

We describe a 30-year-old acute myelomonocytic leukemia patient with abnormal bone marrow eosinophils (AML FAB subtype M4Eo) with extensive extramedullary involvement and, in the absence of an aberration involving chromosome 16, clonal trisomy 21 in the leukemic blast cells.

Key words  Acute myelomonocytic leukemia - AML M4Eo subtype - Cytogenetics - Trisomy 21

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