In this chapter we discuss the following (a) how to setup a development environment for programming the CBE, (b) for PS3 owners details instructions for installing Fedora Core 7 on PS3 and setting up IBM SDK 3.0, tutorials to follow, (c) for Linux users how to setup the MySim IBM Full System Simulator and cross compiler to write, develop and debug applications on the CBE, (d) for Windows users, how to download VMWare Image containing IBM Full System Simulator with IBM SDK 3.0 installed, (e) how to get a remote shell account on POWER.ORG servers at OSU (Oregon, USA), Germany and China, (f) detailed presentation of the CELL Broadband Engine, PPC core, SPU, Element Interconnect Bus, DMA, Mailbox, SIMD, dual-instruction pipeline.