Volume 408, Number 5, 505-508, DOI: 10.1007/BF00705304

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European Society of Pathology

Enzyme histochemical demonstration of hairy cell leukaemia in paraffin-embedded tissue sections

Marianne Hamilton Therkildsen

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Abstract

Hairy cell leukaemia is a form of leukaemia difficult to diagnose since pancytopenia is often present. Hairy cells contain tartrate-resistant acid phosphatase, and this factor is utilised in the diagnosis of the condition. This study confirms that it is also possible to demonstrate tartrate-resistant acid phosphatase in leukaemic infiltrates in formalin fixed paraffin-embedded tissue sections.

Key words  Hairy cell leukaemia - Enzyme histochemistry - Paraffin sections

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