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Methods in Molecular Biology
PCR Mutation Detection Protocols
10.1385/1-59259-273-2:179
Bimal D. M. Theophilus and Ralph Rapley
18. Automated Genotyping Using the DNA MassArray™ Technology

Christian Jurinke3, Dirk van den Boom3, Charles R. Cantor3 and Hubert Köster3

(3)  Sequenom Inc., San Diego, CA
Abstract
The ongoing progress in establishing a reference sequence as part of the Human Genome Project (1) has revealed a new challenge: the large-scale identification and detection of intraspecies sequence variations, either between individuals or populations. The information drawn from those studies will lead to a detailed understanding of genetic and environmental contributions to the etiology of complex diseases.

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