Volume 27, Number 1, 33-35, DOI: 10.1007/BF02348224

A case of pulmonary sclerosing hemangioma
A light microscopic, immunohistochemical and electron microscopic study

Tadahiro Itoh, Hideki Takanari and Ryuichi Yatani

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Abstract

A case of pulmonary sclerosing hemangioma was studied using light microscopic, immunohistochemical and electron microscopic methods. The cytoplasm of the sclerosing hemangioma cells was positive to the anti-lung surfactant apoprotein monoclonal antibody (PE-10). These cells included pale cells of the solid areas, cells covering papillary projections, and cells lining cleft-like spaces. Electron microscopic study showed that the predominant cells included poorly-differentiated pneumocytes and normal Type 2 pneumocytes. We concluded that the sclerosing hemangioma was an epithelial tumor with differentiation towards Type 2 pneumocytes.

Key words  Pulmonary sclerosing hemangioma - Type 2 pneumocyte - Anti-lung surfactant apoprotein monoclonal antibody (PE-10)

A part of this study was presented at the 25th Annual Meeting of the Clinical Electron Microscopy Society of Japan, Matsumoto, September 28–30, 1993.

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