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Abstract

Using a homemade electrogastrography (EGG) system, we studied the characteristics of myoelectrical rhythm in gastric cancer (GC) patients. Based on a short-term Fourier transform, recorded slow waves could be automatically analyzed to obtain the following parameters: dominant frequency/power, percent of normal rhythm (2.4–3.7 cpm), power ratio, etc. Fifty histologically confirmed GC patients (34 men, 16 women) were enrolled before surgical intervention to measure their fasting and postprandial EGG parameters for 30 min. The cancerous parameters of GC patients were then obtained postoperatively. In addition, 46 healthy subjects were enrolled for comparison. When compared to controls, GC patients had the following characteristics: absence of postprandial increase in dominant frequency (GC: 3.04 ± 0.47 vs 3.07 ± 0.44 cpm, NS; controls: 3.02 ± 0.31 vs 3.21 ± 0.25 cpm, P < 0.001),="" marked="" power="" response="" after="" meal="" (p="">< 0.05),="" and="" obvious="" power="" ratio="" (4.58="" ±="" 7.38="" vs="" 2.27="" ±="" 2.05,="" p="">< 0.05).="" multivariate="" analysis="" indicated="" that="" advanced="" gc="" was="" the="" factor="" responsible="" for="" the="" obvious="" dominant="" power="" enhancement="" after="" meal="" (p="">< 0.05).="" other="" demographic,="" clinical,="" and="" cancerous="" factors="" did="" not="" influence="" egg="" parameters.="" we="" conclude="" that="" apparent="" arrhythmia="" is="" not="" encountered="" in="" gc="" patients,="" although="" they="" mainly="" exhibit="" obvious="" postprandial="" power="" response.="" advanced="" gc="" is="" likely="" responsible="" for="" this="" power="" enhancement="" on="" egg="">

electrogastrography - gastric cancer - gastrointestinal motility - Helicobacter pylori - slow wave

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