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Abstract

Using a combination of branching processes and kinetic equations a solution is provided to the problem of describing the size of aggregates formed on cell surfaces when multivalent ligands bind and cross-link multivalent receptors. A criterion is given for the onset of gelation in infinite 2-dimensional systems, which may be relevant to the phenomenon of ligand-induced receptor patching.

Key words  Antigen-antibody reactions - Receptor clustering - Branching processes - Multivalent ligands - Cell surface receptors

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