Piceatannol, isolated from the roots of
Rheum undulatum, prevented oxygen radical formation and inhibited lipid peroxidation; the effective concentrations were 25
M for a radical scavenging assay and 2.1
M for a microsome assay. Using cDNA microarray analysis to determine which genes were modulated by piceatannol, 33 genes were up-regulated while 157 genes were down-regulated in the human gastric cancer cell line.
antioxidant - microarray - piceatannol -
Rheum undulatum L. - RT-PCR