Volume 15, Number 6, 1594-1599, DOI: 10.1245/s10434-008-9903-4

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Compound Muscle Action Potentials and Spontaneous Electromyography Can be Used to Identify and Protect the Femoral Nerve During Resection of Large Retroperitoneal Tumors

Lanjun Guo, John Patrick Clark, Robert S. Warren and Eric K. Nakakura

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Abstract

Background  

Resection of large retroperitoneal neoplasms may injure the femoral nerve, thereby causing a permanent neurological deficit. We used electrical neurophysiological monitoring to identify, map, and preserve the femoral nerve during surgical resection to reduce the risk of neurological deficit.

Methods  

Seven patients with retroperitoneal neoplasms underwent eight resections.
Compound muscle action potentials (CMAPs) were recorded from needle electrodes placed in the iliacus, quadriceps, and sartorius muscles. Spontaneous electromyography (EMG) was contnuously monitored from the same muscle groups. A handheld monopolar stimulator was used to elicit evoked EMG responses to identify and map the course of the femoral nerve. A stimulating strength of 10 mA was used to map the nerve. The stimulation threshold was tested after neoplasm resection to predict postoperative femoral nerve function.

Results  

Electrical stimulation with CMAP recording and a stimulating strength of 10 mA successfully localized the femoral nerve in six cases. Monitoring with a stimulating threshold between 0.6 and 1.6 mA predicted postoperative femoral nerve preservation after tumor resection in four of the six cases.

Conclusion  

Neurophysiological monitoring using CMAP and spontaneous EMG can protect the femoral nerve during resection of large retroperitoneal neoplasms.

Keywords  Retroperitoneal sarcoma - Intraoperative neurophysiological monitoring - Femoral nerve - Electrical stimulation - Electromyography

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