In the southern part of the French Armorican massif, the Ligerian domain is located along the boundary between Gondwana and Armorica. Lithological, geochemical and structural data on the Saint-Georges-sur-Loire Unit, which is the northern part of the Ligerian domain, allow us to distinguish two sub-units. A southern sub-unit, formed by various blocks (chert, limestone, sandstone, rhyolite, mafic rocks) of Silurian to Middle Devonian age included as olistoliths in a Middle-Late Devonian terrigeneous matrix, overthrusts a sandstone-pelite northern sub-unit. Both units experienced two deformation events. The first one is a top-to-the-NW thrusting and the second one is a left-lateral wrenching. The Saint-Georges-sur-Loire Unit is an accretionary prism formed during the Late Devonian closure of the Layon rift, coeval with the main phase of the Variscan orogeny. The Layon rift, which according to the mafic olistoliths was partly floored by oceanic crust, appears as a buffer structural zone that accounts for the lack in Central Brittany of any tectonic or sedimentary echo of the closure of the Medio-European Ocean. The tectonic evolution of the Saint-Georges-sur-Loire Unit supports a polyorogenic model for this part of the Variscan Belt.