Publish/subscribe (pub/sub) is considered a valuable middleware architecture that proliferates loose coupling and leverages reconfigurability and evolution. Up to now, existing pub/sub middleware was optimized for static systems where users as well as the underlying system structure were rather fixed. We study the question whether existing pub/sub middleware can be extended to support mobile and location-dependent applications. We first analyze the requirements of such applications and distinguish two orthogonal forms of mobility: the system-centric physical mobility and an application-centric logical mobility (where users are aware that they are changing location). We introduce location-dependent subscriptions as a suitable means to exploit the power of the event-based paradigm in mobile applications. Briefly spoken, location-dependency refines a subscription to accept only events related to a mobile user's current location. Implementations for both forms of mobility are presented within the content-based pub/sub middleware Rebeca, drawing from its refined routing capabilities (namely, covering and merging).