Skin reactions due to low molecular weight heparin in pregnancy: a strategic dilemma

A. E. M. Verdonkschot, W. L. E. Vasmel, S. Middeldorp and J. T. M. van der Schoot

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Abstract

Introduction

Heparin-induced allergic reactions may cause problems if heparin administration is needed for thrombo-embolic disease in pregnancy.

Case reports

We report two cases of hypersensitivity to low molecular weight heparin (LMWH) in pregnancy.

Discussion

Alternative methods and new antithrombotic agents are discussed.

Keywords Low molecular weight heparin - Pregnancy - Delayed hypersensitivity - Allergy

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