The effect of immunization with embryonic tissue on growth of two syngeneic transplantable tumors was investigated in Syrian hamsters. Immunization of inbred hamsters with embryonic hamster tissue followed by transplantation of continuous lines of syngeneic tumors was shown neither to inhibit nor to stimulate growth of the tumors. It is suggested that embryonic antigens do not participate in the mechanism of transplantation antitumor immunity.
Key Words embryonic antigens - immunization
Laboratory of Immunology of Tumors, Oncologic Scientific Center, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR L. M. Shabad.) Translated from Byulleten'' Éksperimental''noi Biologii i Meditsiny, Vol. 86, No. 7, pp. 57–58, July, 1978.