The rates of improvement of acuity in response to full-time occlusion therapy of 30 esotropic patients with amblyopia were determined. The children's ages at the time of full-time patching ranged from about 3 to 10 years. In keeping with clinical experience, the rate of acuity improvement during patching was slower for older than younger patients. The age-related changes in responsiveness to patching were modeled nonlinearly to provide quantitative guidelines for management of occlusion therapy of esotropic children with amblyopia.