Abstract  A new method for rigorously establishing the existence of a transversal homoclinic orbit to a periodic orbit (or a fixed point) of diffeomorphisms in Rⁿ is presented. It is a computer-assisted technique with two main components. First, a global Newton’s method is devised to compute a suitable pseudo (approximate) homoclinic orbit to a pseudo periodic orbit. Then, a homoclinic shadowing theorem, which is proved herein, is invoked to establish the existence of a true transversal homoclinic orbit to a true periodic orbit near these pseudo orbits.