The proposed use of a more precise standard for glycated (A
1c) and non-glycated haemoglobin would lead to an A
1c value, when expressed as a percentage, that is lower than that currently in use. One approach advocated to address the potential
confusion that would ensue is to replace ‘HbA
1c’ with a new term, ‘A
1c-derived average glucose.’ We review evidence from several sources suggesting that A
1c is, in fact, inherently imprecise as a measure of average glucose, so that the proposed terminology should not be adopted.
Keyword Glycated haemoglobin