The bioavailability of two prazosin formulations was studied in 12 healthy volunteers. 1 Subject left the study. Based on the statistical tests of the pharmacokinetic parameters of prazosin in 11 volunteers, such as
t
1/2,
C
max,
t
max and AUC, it could be concluded that both preparations had comparable bioavailabilities.
Keywords Biological availability - Clinical trials - Pharmacokinetics - Prazosin