With the popularization of networks, digitalization and automation, demand for enterprise informatization becomes more urgent. There are many factors leading to the demand for EIS. Some of the factors are from enterprise development, while others are from policy driven. In this paper, we present a relationship model by using system dynamics method to characterize the cause-result (C-R) of demand drivers of enterprise informatization. Based on the empirical studies, we reveal how the factors affect the demand for enterprise informatization, which form a cluster of causation to be used as the cause variables in our model. This procedure is to settle on the interim variables and result variables, which formed systematic dynamics C-R charts. Questionnaires and interviews from dozens of enterprises, Delphi Expert Decision method are made and analyzed, which verified the relationship between variables. The results presented in this paper provide good insights for the enterprise managers’ optimal decisions.