Morphometric analysis and anatomical correspondence across MR images is important in understanding neurological diseases as
well as brain function. By registering shape models to unseen data, we will be able to segment the brain into its sub-cortical
regions. A Bayesian cost function was derived for this purpose and serves to minimize the residuals to a planar intensity
model. The aim of this paper is to explore the properties and justify the use of the cost function. In addition to a pure
residual term (similar to correlation ratio) there are three additional terms, one of which is a growth term. We show the
benefit of incorporating an additional growth term into a purely residual cost function. The growth term minimizes the size
of the structure in areas of high residual variance. We further show the cost function’s dependence on the local intensity
contrast estimate for a given structure.