Parallel sequential turbocharging systems are able to operate in different modes, which are defined according to the turbochargers that simultaneously boost the engine, and are controlled by means of specific valves. In order to cover the full engine operating range, a smooth transition between turbocharging operating modes must be ensured. However, important disturbances affect both boost and exhaust pressure when shifting the operation mode, thus causing non-negligible torque oscillations. This paper presents different methods for smoothing such undesirable effects during mode transition. Strategies covering optimal synchronization of the control valves, control of the valves’ position, and correction of the injected fuel during the transition are analysed. A fully instrumented passenger car engine is used for illustrating the different torque smoothing methods, and experimental results for transitions during both steady operation and engine accelerations are shown.