OBJECTIVES: To describe the clinical features of adults diagnosed with acute bronchitis, and to identify clinical variables associated
with antibiotic treatment of acute bronchitis.
DESIGN: Prospective, cohort study.
SETTING: Primary care office practices at a group-model HMO in the Denver metropolitan area.
PATIENTS/PARTICIPANTS: Patients were adults seeking care for acute respiratory illnesses. Participating clinicians included internists, family medicine
physicians, nurse practitioners, physician assistants, and registered nurses.
MEASUREMENTS AND MAIN RESULTS: Clinicians voluntarily completed encounter forms for patients presenting with acute respiratory illnesses between February
and May, 1996. Acute bronchitis was the primary diagnosis in 16% of acute respiratory illness visits (n=1,525). The most frequent symptoms of acute bronchitis were cough (92%), phlegm production (63%), “runny nose” (50%), and
throat pain (50%), The most frequent physical examination findings were pharyngeal erythema (45%), cervical lymphadenopathy
(19%), wheezes (18%), and rhonchi (17%). Antibiotics were prescribed to 85% of patients diagnosed with acute bronchitis. Purulent
nasal discharge by patient report, and sinus tenderness on physical examination were moderately associated with antibiotic
treatment (p=.06 and .08, respectively). Antibiotic prescription rates did not vary by patient age or gender, duration of illness, days
of work lost due to illness, or clinician type.
CONCLUSIONS: Acute bronchitis is frequently treated with antibiotics in ambulatory practice. The clinical factors we identified to be
associated with antibiotic use for acute bronchitis appear to play a minor role in explaining the excessive use of antibiotics
for this condition. These findings suggest that clinicians use the diagnosis of acute bronchitis as an indication for antibiotic
treatment, despite clinical trials and expert recommendations to the contrary.
Key Words physician practice patterns - acute respiratory illness - antibiotic treatment - acute bronchitis
This work was supported in part by a National Research Service Award (5 T32 PE 10006-04) (RG) and a Kaiser Permanente of Colorado
Research and Development Grant (RG, PHB).