Volume 150, Number 5, 323-324, DOI: 10.1007/BF01955931

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Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia

T. Hanada, I. Ono, Y. Minosaki, N. Moriyama, S. Nakahara and A. Ohtsu

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Abstract

A recent report demonstrated that t(8;16) (p11;p13) may be linked to acute monocytic leukaemia (AMoL) of differentiated subtype (M5b) with active haemophagocytosis by leukaemic cells. Only two cases of neonatal AMoL with t(8;16)(p11;p13) have been reported; M5b with haemophogocytosis and M5a. We report a case of neonatal AMoL (M5b) with t(8;16)(p11;p13), but haemophagocytosis by the leukaemic cells was not detected.

Key words  Acute monocytic leukaemia - Haemophagocytosis - t(8:16)(p11:p13)

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