In this paper, we propose VirusMeter, a novel and general malware detection method, to detect anomalous behaviors on mobile devices. The rationale underlying VirusMeter is the fact that mobile devices are usually battery powered and any malicious activity would inevitably consume some battery power. By monitoring power consumption on a mobile device, VirusMeter catches misbehaviors that lead to abnormal power consumption. For this purpose, VirusMeter relies on a concise user-centric power model that characterizes power consumption of common user behaviors. In a real-time mode, VirusMeter can perform fast malware detection with trivial runtime overhead. When the battery is charging (referred to as a battery-charging mode), VirusMeter applies more sophisticated machine learning techniques to further improve the detection accuracy. To demonstrate its feasibility and effectiveness, we have implemented a VirusMeter prototype on Nokia 5500 Sport and used it to evaluate some real cellphone malware, including FlexiSPY and Cabir. Our experimental results show that VirusMeter can effectively detect these malware activities with less than 1.5% additional power consumption in real time.