Volume 15, Number 11, 2219-2229, DOI: 10.1007/s00330-005-2826-6

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the European Society of Radiology

Contemporary imaging techniques for the diagnosis of renal artery stenosis

T. Leiner, M. W. Haan, P. J. Nelemans, J. M. A. Engelshoven and G. B. C. Vasbinder

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Abstract

Renal artery stenosis (RAS) is a potentially curable cause of renovascular hypertension (RVH) and is caused by either atherosclerosis or fibromuscular dysplasia (FMD) in the vast majority of patients. Although intra-arterial digital subtraction angiography (IA-DSA) is still considered the standard of reference test for the anatomical diagnosis of RAS, noninvasive techniques such as MR angiography, CT angiography, and color-aided duplex ultrasonography are promising alternatives that also allow functional characterization of RAS. We provide an overview of these techniques and discuss their relative merits and shortcomings. Analysis of high-quality studies shows that both MR and CT angiography are significantly more accurate for the diagnosis of at least 50% atherosclerotic RAS than ultrasonographic techniques. The primary strength of ultrasonography at present is its suggested ability to predict functional recovery based on preinterventional resistance index measurements. A still unresolved issue is the detection of FMD. Because missing RVH may have serious consequences the most important requirement for a screening test is that it has high sensitivity.

Keywords  Renal arteries - Hypertension, renal - Magnetic resonance, vascular studies - Computed tomography, angiography - Kidney, ultrasound

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