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Published in partnership with the
European Association for the Study of Diabetes
For debate
M. A. Nauck and A. El-Ouaghlidi
Journal Article
Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005
J. J. Holst
Diabetologia, 2006, Volume 49, Number 2, Pages 253-260
Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors
J. J. Holst and C. F. Deacon
Diabetologia, 2005, Volume 48, Number 4, Pages 612-615
What mediates the benefits associated with dipeptidyl peptidase-IV inhibition?
B. Ahrén
Diabetologia, 2005, Volume 48, Number 4, Pages 605-607
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
A. Plamboeck, J. J. Holst, R. D. Carr and C. F. Deacon
Diabetologia, 2005, Volume 48, Number 9, Pages 1882-1890
Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes
H.-J. Mest and R. Mentlein
Diabetologia, 2005, Volume 48, Number 4, Pages 616-620
Book Chapter
Coming of Age for the Incretins
Jens Juul Holst and Carolyn F. Deacon
Contemporary Endocrinology, 2008, Controversies in Treating Diabetes, Pages 269-290
How do different GLP-1 mimetics differ in their actions?
Simeon Pierre Choukem and Jean-FranÇois Gautier
Current Diabetes Reports, 2006, Volume 6, Number 5, Pages 365-372
GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors
Bo Ahrén
Current Diabetes Reports, 2007, Volume 7, Number 5, Pages 340-347
Pharmacological profile of ASP8497, a novel, selective, and competitive dipeptidyl peptidase-IV inhibitor, in vitro and in vivo
Yuka Someya, Atsuo Tahara, Ryosuke Nakano, Akiko Matsuyama-Yokono and Itsuro Nagase, et al.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, Volume 377, Number 3, Pages 209-217
Chronic inhibition of dipeptidyl peptidase-IV with ASP8497 improved the HbA1c level, glucose intolerance, and lipid parameter level in streptozotocin–nicotinamide-induced diabetic mice
Akiko Matsuyama-Yokono, Atsuo Tahara, Ryosuke Nakano, Yuka Someya and Masahiko Hayakawa, et al.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2009, Volume 379, Number 2, Pages 191-199
Keywords Dipeptidyl peptidase-IV - Gastric inhibitory polypeptide - Gastroenteropancreatic peptide hormones - Glucagon-like peptide-1 - Incretin - Incretin effect - Oral hypoglycaemic agents - Pharmacokinetics - Proteolytic processing
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