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Pediatric eosinophilic esophagitis: radiologic findings with pathologic correlation
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Original Article
Pediatric eosinophilic esophagitis: radiologic findings with pathologic correlation
Larry A. Binkovitz1, 4 , Emily A. Lorenz1, Carlo Di Lorenzo2 and Samir Kahwash3
| (1) |
Nationwide Children’s Hospital, Columbus, OH, USA |
| (2) |
Department of Gastroenterology, Nationwide Children’s Hospital, Columbus, OH, USA |
| (3) |
Department of Pathology, Nationwide Children’s Hospital, Columbus, OH, USA |
| (4) |
Present address: Mayo Clinic, Division of Pediatric Radiology, E-2, 200 First Ave. SW, Rochester, MN 55901, USA |
Received: 2 July 2009 Revised: 13 October 2009 Accepted: 19 November 2009 Published online: 18 December 2009
Abstract
Background
Eosinophilic esophagitis is increasingly recognized as a cause of dysphagia or food impaction in pediatric patients. It has
a high male predominance and is often associated with a history of allergy or asthma.
Objective
To correlate fluoroscopic findings in eosinophilic esophagitis with the endoscopic and histologic findings.
Materials and methods
We retrospectively reviewed the upper gastrointestinal (UGI) findings of eosinophilic esophagitis and correlated them with
the clinical, endoscopic and histologic findings in a series of 17 children (12 boys, 5 girls).
Results
UGI findings were normal in 12 children, including 4 who had a normal UGI exam after endoscopic disimpaction for an obstructing
food bolus. Five children had strictures identified on UGI: one was demonstrated with endoscopy. This suggests that the impactions
and strictures were due to an esophageal dysmotility rather than a fixed anatomic abnormality.
Conclusion
Because the UGI findings are frequently normal in eosinophilic esophagitis, radiologists need to have a high index of suspicion
for this disease. In children with a strong clinical history, especially impaction in the absence of an esophageal stricture,
endoscopy and biopsy are indicated for further evaluation.
Keywords Eosinophilic - Esophagus - Fluoroscopy - Dysphagia
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