PURPOSE: To examine the features of available Framingham-based risk calculation tools and review their accuracy and feasibility in
clinical practice.
DATA SOURCES:
medline, 1966–April 2003, and the google search engine on the Internet.
TOOL AND STUDY SELECTION: We included risk calculation tools that used the Framingham risk equations to generate a global coronary heart disease (CHD)
risk. To determine tool accuracy, we reviewed all articles that compared the performance of various Framingham-based risk
tools to that of the continuous Framingham risk equations. To determine the feasibility of tool use in clinical practice,
we reviewed articles on the availability of the risk factor information required for risk calculation, subjective preference
for 1 risk calculator over another, or subjective ease of use.
DATA EXTRACTION: Two reviewers independently reviewed the results of the literature search, all websites, and abstracted all articles for
relevant information.
DATA SYNTHESIS: Multiple CHD risk calculation tools are available, including risk charts and computerized calculators for personal digital
assistants, personal computers, and web-based use. Most are easy to use and available without cost. They require information
on age, smoking status, blood pressure, total and HDL cholesterol, and the presence or absence of diabetes. Compared to the
full Framingham equations, accuracy for identifying patients at increased risk was generally quite high. Data on the feasibility
of tool use was limited.
CONCLUSIONS: Several easy-to-use tools are available for estimating patients’ CHD risk. Use of such tools could facilitate better decision
making about interventions for primary prevention of CHD, but further research about their actual effect on clinical practice
and patient outcomes is required.
DISCLOSURE: Drs. Sheridan and Pignone have participated in the development of Heart-to-Heart, one of the risk tools evaluated within.
They have also received speaking and consulting fees from Bayer, Inc. Bayer, Inc. has licensed the Heart-to-Heart tool.
Key words risk assessment - coronary heart disease - Framingham Heart Study