Spinal ganglia L5–L6, together with the mesentery of the large intestine (innervated from these ganglia) and the epithelium of the tongue, were transplanted into the anterior chamber of the eye in cats. After 2 months survival of some of the sensory neurons and intensive regeneration of their nerve fibers were observed. Meanwhile the tissue of the mesentery together with its mechanoreceptors (Pacinian corpuscles) remained intact. The epithelium of the tongue was destroyed. The trophic influence of these particular sensory ganglia on the corresponding tissue ensured the structural integrity of that tissue and of its receptor apparatus. The need for metabolic conformity between the sensory ganglia and the tissue innervated by them is revealed.