In metabolomics, time-resolved, dynamic or temporal data is more and more collected. The number of methods to analyze such
data, however, is very limited and in most cases the dynamic nature of the data is not even taken into account. This paper
reviews current methods in use for analyzing dynamic metabolomic data. Moreover, some methods from other fields of science
that may be of use to analyze such dynamic metabolomics data are described in some detail. The methods are put in a general
framework after providing a formal definition on what constitutes a ‘dynamic’ method. Some of the methods are illustrated
with real-life metabolomics examples.
Keyword Time-resolved - Dynamic systems - Multivariate modeling - Dimension reduction - Time series analysis - Basis functions