We consider a single machine earliness/tardiness scheduling problem with general weights, ready times and due dates. Our solution approach is based on a time-indexed preemptive relaxation of the problem. For the objective function of this relaxation, we characterize cost coefficients that are the best among those with a piecewise linear structure with two segments. From the solution to the relaxation with these best objective function coefficients, we generate feasible solutions for the original non-preemptive problem. We report extensive computational results demonstrating the speed and effectiveness of this approach.