Volume 38, Number 2, 264-268, DOI: 10.1023/A:1015534221121

Reactions of Aliphatic Diazo Compounds: V. Reaction of Methyl Diazoacetate with Imides of Itaconic Acid

A. P. Molchanov, A. V. Stepakov and R. R. Kostikov

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Abstract

Methyl diazoacetate regioselectively adds to N-substituted imides of itaconic acid to afford 2-pyrazolines, methyl 7-aryl-6,8-dioxo-1,2,7-triazaspiro[4.4]non-2-ene-3-carboxylates that in reaction with halogens (Cl2, Br2) yield methyl 5-aryl-1-halo-4,6-dioxo-5-azaspiro[2.4]heptane-1-carboxylates as a mixture of syn- and anti-isomers.

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