Relevant changes in cerebral circulation occur during “Piggy Back” liver transplantation. Particularly at the washout-reperfusion
time the cerebral perfusion suddenly changes from its lowest to its highest values. Further investigation is required to evaluate
whether patients with the greatest change in cerebral oxygenation at this time point will suffer neurological complications
after transplantation.
It is remarkable that TOI and THI levels are higher in the most compromised patients, perhaps because of an increased CO and,
mainly, because of a decreased vascular resistance.