Purpose
To identify the practices of ophthalmologists when undertaking glaucoma surgery on patients concurrently using warfarin or
acetylsalicylic acid (aspirin).
Methods
A questionnaire was designed to examine perioperative management of patients being treated with warfarin and aspirin prior
to and during glaucoma surgery. The questionnaire was posted with stamped self-addressed envelopes to all glaucoma specialists
registered on a glaucoma shared care scheme database.
Results
Of the 93 eligible participants, 64 returned a completed questionnaire, representing a response rate of 68.8%. Twenty-one
surgeons (32.8%) routinely stopped warfarin before surgery. Mean time prior to surgery of drug cessation was 4 days (range
2–7). Three surgeons (14.3%) routinely commenced heparin if they stopped warfarin. Ten (47.6%) never used heparin, while the
remaining eight (38.1%) would use heparin depending upon the indication for anticoagulation. Forty-two surgeons (81.25%)were
happy to operate only at an INR ≤3 at the time of surgery. The remainder (18.75%) were happy to operate at higher INRs, including
two surgeons (3.1%) who would operate at any level. Twenty surgeons (31.2%) routinely stopped aspirin before surgery, while
the rest did not. Of those who stopped aspirin, the mean time prior to surgery was 7.1 days (range 4–14 days).
Conclusions
The majority of surgeons do not stop warfarin or aspirin prior to glaucoma surgery. There is a great diversity in current
practice with regard to the management of anticoagulant therapy prior to glaucoma surgery amongst glaucoma surgeons in England.
Currently there is little information available to offer definitive guidance.
Keywords Glaucoma - Trabeculectomy - Anticoagulation - Warfarin - Aspirin