Performance of homosexual and heterosexual men and women on two motor tasks which reliably demonstrate sex differences in opposite directions was examined. A Throw-to-Target Task and the Purdue Pegboard were administered to undergraduate students matched for age and program of study. A two-way ANOVA (Sex × Sexual Orientation) of the Throw data showed a significant interaction,F(1, 90) = 16.22,p 0.001, and a trend for an effect of sex,F(1, 90) = 3.72,p < 0.06.="" heterosexual="" men="" outperformed="" heterosexual="" women,="" whereas="" gay="" men="" threw="" less="" accurately="" and="" lesbians="" tended="" to="" throw="" more="" accurately="" than="" their="" heterosexual="" counterparts.="" differences="" in="" sports="" history="" or="" hand="" strength="" did="" not="" account="" for="" these="" effects.="" analysis="" of="" the="" pegboard="" scores="" found="" no="" interaction="" or="" main="" effect="" of="" sexual="" orientation,="" but="" the="" effect="" of="" sex="" was="">F(1,63) = 7.01,p 0.02. Regardless of sexual orientation, women outperformed men and this difference remained significant even when a measure of finger size was partialed out. This study provides new evidence suggesting an association between sexual orientation and motor-performance profiles. As with cognitive tasks, the motor-performance profiles of homosexuals are composites of some male-typical and some female-typical abilities. To the extent that sociological factors have been controlled, the study suggests that both sexual orientation and motor/cognitive predispositions may have early biological contributions.