Aims
To assess patient satisfaction after intravitreous plasminogen activator injections for subretinal hemorrhages secondary to
age-related macular degeneration (AMD) and to analyse how it relates to the patients' postoperative visual and functional
abilities. Further, to suggest ways to improve in-patient management and thereby treatment satisfaction.
Methods
A consecutive series of 101 patients with a subretinal hemorrhage of at least one disk diameter were enrolled in this longitudinal
prospective study conducted during 2001–2004. After complete preoperative eye examination all patients were treated with intravitreal
injection of 25 μg recombinant tissue plasminogen activator (rTPA) and 0.5 ml sulphur hexafluoride gas (SF6), followed by
face-down positioning for 1 week. Patient satisfaction was assessed using standardised questionnaires administered postoperatively
at 4 and 12 months. Outcome measures were: (1) responses to the patient satisfaction survey, (2) degree of satisfaction with
in-patient management, (3) subjective change in the patients' functional status, and (4) visual acuity results.
Results
Whereas the patients' actual functional status deteriorated from a median value of 2.4 at 4 months to 3.4 at 12 months, their
recall of their preoperative functional status shifted from a median value of 4.2 to to 2.3, consecutively. Twelve months
after treatment, 75% of patients reported an improved visual acuity, however, only 12% reported satisfaction with treatment.
67.4–87% of patients were dissatisfied with various areas of in-patient management.
Conclusions
Satisfaction with plasminogen activator injection treatment is low even though patients experience an improved visual and
functional status at 12 months. This suggests that the current system requires improvement in certain areas such as in-patient
management.
Keywords Intravetreous injection - Plasminogen activator injection - Subretinal hemmorhage - Age-related macular degeneration - Patients’ satisfaction