During the last years the requirements on modern cell culture have rapidly increased, comprising quality control, global administration and global availability of cell lines. To meet these demands we developed CryoStock as a new software tool for cell culture management. This application combines a database for the storage of stocks and a LIMS for tracking all tasks during handling and transfer of cell lines. The data collected during the cell culture process can be used to follow parent/child relationships and to generate user friendly queries and reports. CryoStock will put another layer of quality on our cell culture handling to increase reproducibility and outcome of cell-based assays and to accelerate the knowledge transfer among Aventis' scientists.